Depletion-induced interactions modulate nanoscale protein diffusion in polymeric crowder solutions
M. Dargasz, N. D. Anthuparambil, S. Retzbach, A. Girelli, S. Timmermann, ...
DOI: 10.1073/pnas.2524733123Profile
My work focuses on understanding micro-scale dynamics in soft matter and biological systems using coherent X-ray scattering methods. I develop automated analysis workflows for synchrotron datasets and contribute to tools supporting the international XPCS community.
Selected Publications
Lipoprotein diffusion in dense yolk plasma is governed by softness, hydrodynamics, and caging: Insights from MHz-XPCS
N. D. Anthuparambil, M. Dargasz, S. Timmermann, A. Girelli, S. Retzbach, ...
DOI: 10.1073/pnas.2519681123Coherent X-rays reveal anomalous molecular diffusion and cage effects in crowded protein solutions
A. Girelli, M. Bin, M. Filianina, M. Dargasz, N. D. Anthuparambil, J. Möller, ...
DOI: 10.1038/s41467-025-66972-6Softness and Hydrodynamic Interactions Regulate Lipoprotein Transport in Crowded Yolk Environments
N. D. Anthuparambil, M. Dargasz, S. Timmermann, A. Girelli, S. Retzbach, ...
DOI: 10.48550/arXiv.2505.22520Dynamic Metadata Schemes in the Neutron and Photon Science Communities: A Case Study of X-Ray Photon Correlation Spectroscopy
A. Tosson, M. Reza, C. Gutt
DOI: 10.48550/arXiv.2501.16814Beamtime & Synchrotron Experiments
Deutsches Elektronen-Synchrotron (DESY) PETRA III · P10 Beamline
In-situ SAXS/USAXS-XPCS experiments on the influence of NaCl ions in denaturation and gelation processes.
European Synchrotron Radiation Facility (ESRF) · ID10 / ID02 Beamlines
SAXS, USAXS, and XPCS experiments for soft matter and protein dynamics.
European X-Ray Free-Electron Laser Facility (European XFEL) · MID Instrument
MHz-XPCS experiments and high-rate coherent scattering data analysis.
DAPHNE4NFDI
Development and implementation of standardized data-analysis pipelines for the global XPCS community.
Professional Appointments
Postdoctoral Researcher · DESY (PHOTONIC Project)
- API development for experimental big data streaming from DESY facilities.
Research Assistant · University of Siegen
- Research on protein dynamics using XPCS.
- Development of online tools and analysis workflows for the XPCS community.
- Contribution to DAPHNE4NFDI scientific data infrastructure.
Research Assistant · RWTH Aachen University
- CUDA programming and parallel computing.
- Development of quantum chemistry code in Fortran.
- Research in theoretical quantum chemistry.
Data Analyst · ATLAS Group, CERN
- Generated Monte Carlo and data events for Z-boson decay.
- Measured fake electrons using tag-and-probe methods.
- Developed analysis tools in C/C++, Python, CMake, ROOT, and RooFit.